Bronchodilator effects of the H1 receptor antagonist--clemastine.
نویسندگان
چکیده
We investigated the specific H1 receptor antagonist, clemastine, in 15 children with asthma. In the respiratory unit, clemastine was an effective bronchodilator but in a clinical trial we could not show any significant benefit compared with placebo.
منابع مشابه
The Comparative Effects of Four Antihistamines on Isolated Rat Atria
It has been reported that some of H1 receptor antagonists have important effects on cardiovascular system. Terfenadine as a non-sedative H1 receptor antagonist has an arrhythmogenic activity. In this study we have shown the effects of four antihistamine drugs: terfenadine, loratadine, clemastine and diphenhydramine, on the rate and contractions of isolated rat atria. Terfenadine (1-10 µM) cause...
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ورودعنوان ژورنال:
- Archives of disease in childhood
دوره 58 4 شماره
صفحات -
تاریخ انتشار 1983